Since these compounds in grapefruits greatly decrease the rate of breakdown, repeated doses can lead to much higher doses of the drug in the bloodstream, in turn potentially leading to harmful side effects
References: Blundell J, Finlayson G, Axelsen M, Flint A, Gibbons C, Kvist T, et al
The BPCIA Patent Dance Mechanics: Step-by-Step Timeline and Strategic Choices Why the 2017 Sandoz v
The Side Effects of Ozempic and GP-1 Receptor Agonists Beyond the considerations discussed above, these medications do come with some health complications
The mechanism involves suppression of NF-kB signaling, one of the master switches of inflammation throughout the body
"They're not going to be paying as much for hypertension drugs